A single molecule is not a synthetically manufactured nanomaterial, but what about compounds of 10 or 100 molecules?

With this and other borderline cases, it should be noted that when using the precautionary matrix one is not concerned with the exact definition of “nano”, but more about determining whether a possible nanospecific need for action exists. With this in mind, in case of doubt the use of the precautionary matrix for a giant molecule or agglomerates of single molecules is not wrong.